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DTSTAMP:20260524T061848Z
DESCRIPTION:Edith Hamel\, PhD\n\nProfessor Department of Neurology & Neuros
 urgery\n\nMNI The Montreal Neurological Institute and Hospital\n\n91ɬÂþ U
 niversity\n\nTitle: Vascular factors in Alzheimer's disease: interventions
  and cognitive benefits\n\n \n\nMonday\, February 6\, 2017\n\n12:00pm  Roo
 m 1345\n\nMcIntyre Medical Sciences Building\n\n/phar
 ma/newsevents/seminar-schedule\n\n \n\nBio\n\nMy research focuses on the i
 nteractions between neurons\, astrocytes \, and microvessels that assure a
  proper blood supply to active brain areas\, a phenomenon known as neurova
 scular coupling\, which is at the basis of the signals used in brain imagi
 ng studies. Several neurological conditions\, such as Alzheimer's disease\
 , are associated with a cerebrovascular pathology and display defective ne
 urovascular coupling responses. We use in vivo neuronal simulation paradig
 ms\, record the evoked perfusion response and identify anatomically the ne
 urons that generate this response\, and record changes in their activity. 
 We manipulate their mediators pharmacologically to define whether neurons 
 act directly on blood vessels or indirectly through astroglial messengers.
  We test the hypothesis that rescuing cerebrovascular function will have b
 enefits in Alzheimer's disease\, and evaluate how risk factors such as hyp
 ertension and hypercholesterolemia can interact in the disease process to 
 accelerate or trigger the manifestation of Alzheimer's disease.\n
DTSTART:20170206T170000Z
DTEND:20170206T180000Z
LOCATION:CA\, QC\, Montreal\, H2X 3P8\, New Residence Hall\, 3625 avenue du
  Parc
SUMMARY:Edith Hamel\, PhD Professor Department of Neurology & Neurosurgery\
 , MNI The Montreal Neurological Institute and Hospital
URL:/pharma/channels/event/edith-hamel-phd-professor-d
 epartment-neurology-neurosurgery-mni-montreal-neurological-institute-and-2
 65154
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